Treatment for Breast Cancer1

There are different treatment options for breast cancer.

The standard treatment includes:

Surgery

Most patients with breast cancer have surgery to remove the tumor

Types of surgeries include the following:

Breast-conserving surgery is an operation to remove the cancer and some normal tissue around it, but not removing the breast itself. This type of surgery may also be called lumpectomy, partial mastectomy, segmental mastectomy, quadrantectomy, or breast-sparing surgery

Surgery to remove the whole breast that has cancer. This procedure is also called a simple mastectomy

This surgery is done to remove the whole breast that has cancer, and many of the lymph nodes under the arm, the lining over the chest muscles, and sometimes, part of the chest wall muscles


Radiation therapy

It is a cancer treatment that makes use of high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing.

Types of radiation therapy:

Internal radiation therapy

(using a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer)


Chemotherapy

Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells. The mechanisms involved are either killing the cells or stopping them from dividing. Chemotherapy may use drugs taken orally or by injecting them into a vein or muscle.


Hormone therapy

Hormone therapy is a cancer treatment that removes hormones or blocks their action and stops cancer cells from growing. It can include:

Hormone therapy with tamoxifen (for patients with early localized breast cancer that can be removed by surgery and those with metastatic breast cancer)

Using a luteinizing hormone-releasing hormone (LHRH) agonist(for premenopausal women recently diagnosed with hormone receptor positive breast cancer.)

Hormone therapy with an aromatase inhibitor( for postmenopausal women who have hormone receptor positive breast cancer)


Targeted therapy

Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific cancer cells. They are less harmful to normal cells than chemotherapy or radiation therapy

Types of targeted therapies used in the treatment of breast cancer:

  • Monoclonal antibodies
  • Tyrosine kinase inhibitors
  • Cyclin-dependent kinase inhibitors
  • Mammalian target of rapamycin (mTOR) inhibitors, and
  • PARP (Poly adenosine diphosphate-ribose polymerase) inhibitors
  • Antibody drug conjugates (ADC)

Immunotherapy

It is a type of therapy that uses substances to stimulate or suppress the immune system to help the body fight cancer. In essence, it is a treatment method that uses the patient’s own immune system to fight cancer. The substances used to boost, direct, or restore the body’s natural defenses against cancer are made either in our body or in the laboratory

    References
  1. Breast Cancer Treatment (Adult) Available at https://www.cancer.gov/types/breast/patient/breast-treatment-pdq#_185 Accessed on 28 July 2021